183200-12-6

183200-12-6 structure

Name: Guanylin(human)
Chemical Name: Guanylin (human)
CAS Number: 183200-12-6
Molecular Formula: C₅₈H₈₇N₁₅O₂₁S₄
Molecular Weight: 1458.66000
Catalog: Signaling Pathways GPCR/G Protein Guanylate Cyclase
Create Date: 2016-11-14 12:19:24
Modify Date: 2024-01-02 11:21:00
Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].

Name	Guanylin (human)
Synonyms	h-pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys-oh pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys PGTCEICAYAACTGC

Description	Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase
References	[1]. M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51. [2]. J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75.