121034-89-7

121034-89-7 structure

Name: IEM-1460
Chemical Name: 5-(1-adamantylmethylamino)pentyl-trimethylazanium,bromide,hydrobromide
CAS Number: 121034-89-7
Molecular Formula: C₁₉H₃₈Br₂N₂
Molecular Weight: 454.33
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2016-04-25 15:37:33
Modify Date: 2024-01-03 12:46:29
IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].

Name	5-(1-adamantylmethylamino)pentyl-trimethylazanium,bromide,hydrobromide
Synonyms	5-[(Adamantan-1-ylmethyl)amino]-N,N,N-trimethyl-1-pentanaminium bromide hydrobromide (1:1:1) 1-Pentanaminium, N,N,N-trimethyl-5-[(tricyclo[3.3.1.1]dec-1-ylmethyl)amino]-, bromide, hydrobromide (1:1:1) 5-[(Adamantan-1-ylmethyl)amino]-N,N,N-trimethylpentan-1-aminium bromide hydrobromide (1:1:1) Iem 1460 Tocris-1636

Description	IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Schlesinger F, et al. Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. Br J Pharmacol. 2005 Jul;145(5):656-63.