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915769-50-5

915769-50-5 structure
915769-50-5 structure
  • Name: Dovitinib lactate
  • Chemical Name: CHIR-258
  • CAS Number: 915769-50-5
  • Molecular Formula: C24H29FN6O5
  • Molecular Weight: 500.523
  • Catalog: API Antineoplastic agents Tinic antineoplastic agents
  • Create Date: 2018-07-24 16:37:55
  • Modify Date: 2024-01-21 17:02:56
  • Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.

Name CHIR-258
Synonyms Dovitinib lactate
2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (1:1:1)
Unii-69vky8p7ea
Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone, hydrate (1:1:1)
dovitinib
TKI-258
Molecular Formula C24H29FN6O5
Molecular Weight 500.523
Exact Mass 500.218353
PSA 160.80000
LogP 2.51610
Storage condition -20℃