852433-84-2

852433-84-2 structure

Name: Dovitinib (TKI-258) Dilactic Acid
Chemical Name: 2-Hydroxypropanoic acid-4-amino-5-fluoro-3-[5-(4-methyl-1-piper azinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1)
CAS Number: 852433-84-2
Molecular Formula: C₂₇H₃₃FN₆O₇
Molecular Weight: 572.59
Catalog: Biochemical Inhibitor Angiogenesis FLT3 inhibitor
Create Date: 2018-10-04 16:31:25
Modify Date: 2024-01-03 17:07:59
Dovitinib (dilactic acid) is an orally active inhibitor of VEGF kinase. Dovitinib (dilactic acid) inhibits receptor tyrosine kinases (RTKs) involved in solid and hematologic cancers and tumor angiogenesis[1].

Name	2-Hydroxypropanoic acid-4-amino-5-fluoro-3-[5-(4-methyl-1-piper azinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1)
Synonyms	Dovitinib (TKI-258) Dilactic Acid Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1) Dovitinib Dilactic acid 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone (2:1) TKI258 Dilactic acid Dovitinib Dilacticacid

Description	Dovitinib (dilactic acid) is an orally active inhibitor of VEGF kinase. Dovitinib (dilactic acid) inhibits receptor tyrosine kinases (RTKs) involved in solid and hematologic cancers and tumor angiogenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
References	[1]. Zhu, S., et al. The Chemical Development of CHIR-258. CHIMIA International Journal for Chemistry, 60(9), 584–592.