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80-99-9

80-99-9 structure
80-99-9 structure
  • Name: Lathosterol
  • Chemical Name: 5α-cholest-7-en-3β-ol
  • CAS Number: 80-99-9
  • Molecular Formula: C27H46O
  • Molecular Weight: 386.65400
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2019-02-22 17:06:26
  • Modify Date: 2024-01-03 18:27:54
  • Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.

Name 5α-cholest-7-en-3β-ol
Synonyms Cholest-7-en-3beta-ol
Cholest-7-en-3-ol
5alpha-Cholest-7-en-3beta-ol
(3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
5alpha-cholest-7-en-3beta-ol
7-cholestenol
Lathosterol
Description Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Kempen HJ, et al. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988 Sep;29(9):1149-55.

Density 0.98 g/cm3
Boiling Point 479.4ºC
Molecular Formula C27H46O
Molecular Weight 386.65400
Flash Point 208.9ºC
Exact Mass 386.35500
PSA 20.23000
LogP 7.38870
Index of Refraction 1.525
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FZ7000000
CHEMICAL NAME :
5-alpha-Cholest-7-en-3-beta-ol
CAS REGISTRY NUMBER :
80-99-9
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H46-O
MOLECULAR WEIGHT :
386.73
WISWESSER LINE NOTATION :
L E5 B666 IUTJ A1 E1 FY1&3Y1&1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg/9W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 19,977,1957
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS FZ7000000