Name | medronic acid |
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Synonyms |
MDP,Medronic acid
phosphonomethylphosphonic acid MDP,Medronic acid,Methylenediphosphonic acid methanediylbis(phosphonic acid) MDP~Medronicacid Medronic Acid Methylenediphosphonic acid Methylenebiphosphonic Acid methylene biphosphonate acide méthanediylbis(phosphonique) Methanebisphosphonic Acid Methanediphosphonic Acid Medronic acid [USAN:BAN:INN] METHYLENEBISPHOSPHONIC ACID Medronic methylenediphosphonate Phosphonic acid, methylenebis- EINECS 217-851-0 MDP Methylenebis(phosphonic acid) MFCD00002139 Methandiylbis(phosphonsäure) |
Description | Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging. |
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Related Catalog | |
References |
Density | 2.1±0.1 g/cm3 |
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Boiling Point | 583.2±60.0 °C at 760 mmHg |
Melting Point | 197-199 °C(lit.) |
Molecular Formula | CH6O6P2 |
Molecular Weight | 176.002 |
Flash Point | 306.5±32.9 °C |
Exact Mass | 175.963959 |
PSA | 134.68000 |
LogP | -4.11 |
Vapour Pressure | 0.0±3.5 mmHg at 25°C |
Index of Refraction | 1.550 |
Storage condition | 2-8°C |
Symbol |
GHS05 |
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Signal Word | Danger |
Hazard Statements | H314 |
Precautionary Statements | P280-P305 + P351 + P338-P310 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | C: Corrosive; |
Risk Phrases | R34 |
Safety Phrases | S26-S36/37/39-S45 |
RIDADR | UN 3261 8/PG 3 |
WGK Germany | - |
RTECS | SZ9138000 |
Packaging Group | III |
Hazard Class | 8 |
HS Code | 2931900090 |
~97% 1984-15-2 |
Literature: Rubino, Maria Teresa; Agamennone, Mariangela; Campestre, Cristina; Campiglia, Pietro; Cremasco, Viviana; Faccio, Roberta; Laghezza, Antonio; Loiodice, Fulvio; Maggi, Dariana; Panza, Emilia; Rossello, Armando; Tortorella, Paolo ChemMedChem, 2011 , vol. 6, # 7 p. 1258 - 1268 |
~93% 1984-15-2 |
Literature: Bulman Page, Philip C.; McKenzie, Michael J.; Gallagher, James A. Synthetic Communications, 2002 , vol. 32, # 2 p. 211 - 218 |
~99% 1984-15-2 |
Literature: Mohamady, Samy; Jakeman, David L. Journal of Organic Chemistry, 2005 , vol. 70, # 25 p. 10588 - 10591 |
~% 1984-15-2 |
Literature: Journal of the American Chemical Society, , vol. 83, p. 1722 - 1726 |
~% 1984-15-2 |
Literature: Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 31, p. 153 - 157 |
~% 1984-15-2 |
Literature: Phosphorus, Sulfur and Silicon and Related Elements, , vol. 161, p. 75 - 96 |
HS Code | 2931900090 |
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Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |