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1984-15-2

1984-15-2 structure
1984-15-2 structure

Name medronic acid
Synonyms MDP,Medronic acid
phosphonomethylphosphonic acid
MDP,Medronic acid,Methylenediphosphonic acid
methanediylbis(phosphonic acid)
MDP~Medronicacid
Medronic Acid
Methylenediphosphonic acid
Methylenebiphosphonic Acid
methylene biphosphonate
acide méthanediylbis(phosphonique)
Methanebisphosphonic Acid
Methanediphosphonic Acid
Medronic acid [USAN:BAN:INN]
METHYLENEBISPHOSPHONIC ACID
Medronic
methylenediphosphonate
Phosphonic acid, methylenebis-
EINECS 217-851-0
MDP
Methylenebis(phosphonic acid)
MFCD00002139
Methandiylbis(phosphonsäure)
Description Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging.
Related Catalog
References

[1]. Ohta Y, et al. Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive MethylenediphosphonicAcid. Mass Spectrom (Tokyo). 2014;3(1):A0031.

Density 2.1±0.1 g/cm3
Boiling Point 583.2±60.0 °C at 760 mmHg
Melting Point 197-199 °C(lit.)
Molecular Formula CH6O6P2
Molecular Weight 176.002
Flash Point 306.5±32.9 °C
Exact Mass 175.963959
PSA 134.68000
LogP -4.11
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.550
Storage condition 2-8°C
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C: Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3261 8/PG 3
WGK Germany -
RTECS SZ9138000
Packaging Group III
Hazard Class 8
HS Code 2931900090

~97%

1984-15-2 structure

1984-15-2

Literature: Rubino, Maria Teresa; Agamennone, Mariangela; Campestre, Cristina; Campiglia, Pietro; Cremasco, Viviana; Faccio, Roberta; Laghezza, Antonio; Loiodice, Fulvio; Maggi, Dariana; Panza, Emilia; Rossello, Armando; Tortorella, Paolo ChemMedChem, 2011 , vol. 6, # 7 p. 1258 - 1268

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1984-15-2 structure

1984-15-2

Literature: Bulman Page, Philip C.; McKenzie, Michael J.; Gallagher, James A. Synthetic Communications, 2002 , vol. 32, # 2 p. 211 - 218

~99%

1984-15-2 structure

1984-15-2

Literature: Mohamady, Samy; Jakeman, David L. Journal of Organic Chemistry, 2005 , vol. 70, # 25 p. 10588 - 10591

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1984-15-2 structure

1984-15-2

Literature: Journal of the American Chemical Society, , vol. 83, p. 1722 - 1726

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1984-15-2 structure

1984-15-2

Literature: Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 31, p. 153 - 157

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1984-15-2 structure

1984-15-2

Literature: Phosphorus, Sulfur and Silicon and Related Elements, , vol. 161, p. 75 - 96
HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%