52432-72-1

52432-72-1 structure
52432-72-1 structure

Name 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate,2-hydroxypropane-1,2,3-tricarboxylic acid
Synonyms Bio-0361
HMS3264M05
Oxeladin citrate salt
oxeladin dihydrogen citrate
oxeladin citrate
Oxeladin-zitrat
Oxeladin (citrate)
Description Oxeladin citrate is a cough suppressant, is a highly potent and effective drug used to treat all types of cough of various etiologies.
Related Catalog
Boiling Point 609.1ºC at 760 mmHg
Melting Point 90-91°
Molecular Formula C26H41NO10
Molecular Weight 527.60400
Flash Point 322.2ºC
Exact Mass 527.27300
PSA 170.90000
LogP 2.39750
Storage condition -20℃
Water Solubility Freely soluble in water, slightly to very slightly soluble in ethyl acetate.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ET1760000
CHEMICAL NAME :
Butyric acid, 2-ethyl-2-phenyl-, 2-(2-(diethylamino)ethoxy)ethyl ester, citrate
CAS REGISTRY NUMBER :
52432-72-1
LAST UPDATED :
198910
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H33-N-O3.C6-H8-O7
MOLECULAR WEIGHT :
527.68
WISWESSER LINE NOTATION :
2X2&R&VO2O2N2&2 &QV1XQVQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
183 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
244 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 82,1314,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301 + H311 + H331
Precautionary Statements Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases 23/24/25
Safety Phrases 36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS ET1760000