743456-83-9
743456-83-9 structure
- Name: 2-[(2-Bromobenzyl)oxy]benzoic acid
- Chemical Name: 2-[(2-Bromobenzyl)oxy]benzoic acid
- CAS Number: 743456-83-9
- Molecular Formula: C14H11BrO3
- Molecular Weight: 307.139
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2017-06-12 19:12:17
- Modify Date: 2024-03-11 07:36:25
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ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7[1].
| Name | 2-[(2-Bromobenzyl)oxy]benzoic acid |
|---|---|
| Synonyms |
2-(2-bromobenzo[d]thiazol-6-yl)acetonitrile
2-(2-bromoacetamido)-3-cyano-4,5-dimethylacetophenone Acetamide,N-(6-acetyl-2-cyano-3,4-dimethylphenyl)-2-bromo 2-[(2-Bromobenzyl)oxy]benzoic acid 2-(2-bromobenzyloxy)benzoic acid Benzoic acid, 2-[(2-bromophenyl)methoxy]- |
| Description | ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild type, Ras protein wild type, GTP-binding protein (Rab7), Rac1 protein activated mutant, Rac1 protein wild type, and Ras protein activated mutant with EC50 values of 50.11 nM, 102.32 nM, 109.64 nM, 20.41 nM, 81.28 nM, 151.35 nM, and 93.32 nM, respectively[1]. |
| References |
[1]. Zurab Surviladze, et al. Three small molecule pan activator families of Ras-related GTPases. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 445.4±25.0 °C at 760 mmHg |
| Molecular Formula | C14H11BrO3 |
| Molecular Weight | 307.139 |
| Flash Point | 223.2±23.2 °C |
| Exact Mass | 305.989136 |
| PSA | 46.53000 |
| LogP | 3.92 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.629 |
| HS Code | 2918990090 |
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| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |