2167-85-3

2167-85-3 structure
2167-85-3 structure
  • Name: Pipazethate
  • Chemical Name: 2-(2-piperidin-1-ylethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate
  • CAS Number: 2167-85-3
  • Molecular Formula: C21H25N3O3S
  • Molecular Weight: 399.50700
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
  • Create Date: 2018-09-20 15:27:46
  • Modify Date: 2024-01-14 17:15:36
  • Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].

Name 2-(2-piperidin-1-ylethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate
Synonyms 4-Aza-phenothiazin-10-carbonsaeure-piperidino-aethoxy-aethylester
Pipazetato [INN-Spanish]
Pipazetate
Pipazetatum [INN-Latin]
pipazethate
Theratuss
benzo[b]pyrido[2,3-e][1,4]thiazine-10-carboxylic acid 2-(2-piperidin-1-yl-ethoxy)-ethyl ester
Lenopect
Description Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].
Related Catalog
Density 1.26g/cm3
Boiling Point 553.3ºC at 760mmHg
Molecular Formula C21H25N3O3S
Molecular Weight 399.50700
Flash Point 288.4ºC
Exact Mass 399.16200
PSA 80.20000
LogP 4.32630
Vapour Pressure 2.76E-12mmHg at 25°C
Index of Refraction 1.612

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU8485000
CHEMICAL NAME :
10H-Pyrido(3,2-b)(1,4)benzothiazine-10-carboxylic acid, 2-(2-(1-piperidinyl)ethoxy) ethyl ester
CAS REGISTRY NUMBER :
2167-85-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H25-N3-O3-S
MOLECULAR WEIGHT :
399.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
94647 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,189,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13140 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,189,1970
Precursor  3

DownStream  0