80832-44-6

80832-44-6 structure

Name: Pyracrenic acid
Chemical Name: (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
CAS Number: 80832-44-6
Molecular Formula: C₃₉H₅₄O₆
Molecular Weight: 618.84
Create Date: 2017-12-27 02:43:40
Modify Date: 2024-01-09 20:26:10
Pyracrenic acid is an elastase inhibitor (IC50 = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity[1][2].

Name	(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
Synonyms	Pyracrenic acid Betulinic Acid 3Beta-Caffeate betulinic acid 3beta-transcaffeate

Description	Pyracrenic acid is an elastase inhibitor (IC50 = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Elastase Research Areas >> Inflammation/Immunology
In Vitro	Pyracrenic acid 具有非常强的弹性蛋白酶抑制活性，IC50 值为 1.5 µg/mL (2.42 µM)[2]。
References	[1]. Otsuka H, et al. Studies on anti-inflammatory agents. V. A new anti-inflammatory constituent of Pyracantha crenulata roem. Chem Pharm Bull (Tokyo). 1981 Nov;29(11):3099-104. [2]. Kim J H, et al. Compounds with elastase inhibition and free radical scavenging activities from Callistemon lanceolatus. J Med Plants Res. 2009, 3(11): 914-920.

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DownStream 1
472-15-1