80971-60-4
80971-60-4 structure
- Name: n-Butyl β-D-fructofuranoside
- Chemical Name: (2R,3S,4S,5R)-2-butoxy-2,5-bis(hydroxymethyl)oxolane-3,4-diol
- CAS Number: 80971-60-4
- Molecular Formula: C10H20O6
- Molecular Weight: 236.26200
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2017-07-12 21:12:52
- Modify Date: 2024-01-11 15:06:48
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n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research[1].
| Name | (2R,3S,4S,5R)-2-butoxy-2,5-bis(hydroxymethyl)oxolane-3,4-diol |
|---|---|
| Synonyms | Butyl fructofuranoside |
| Description | n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research[1]. |
|---|---|
| Related Catalog | |
| Target |
Bax Bcl-2 |
| In Vitro | n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells[1]. n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis[1]. Cell Viability Assay[1] Cell Line: Bel-7402 cells Concentration: 0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL Incubation Time: 24, 48 and 72 hours Result: Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner. Cell Cycle Analysis[1] Cell Line: Bel-7402 cells Concentration: 0, 50 and 75 μg/mL Incubation Time: 24, 48 and 72 hours Result: Induced cell cycle arrest at G0/G1 phase. Western Blot Analysis[1] Cell Line: Bel-7402 cells Concentration: 23.6 μg/mL Incubation Time: 0, 24, 48 and 72 hours Result: Decreased Bcl-2 and increased Bax and p53 levels in a time manner. |
| References |
| Molecular Formula | C10H20O6 |
|---|---|
| Molecular Weight | 236.26200 |
| Exact Mass | 236.12600 |
| PSA | 99.38000 |