Name | dabsyl chloride |
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Synonyms |
EINECS 260-235-1
4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonyl chloride MFCD00007444 |
Description | Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. |
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Related Catalog | |
In Vitro | Dabsyl chloride can give rise to mono-Dabsyl and bis-Dabsyl derivatives in the presence of multiple amino groups. Furthermore with respect to OPA derivatization, Dabsyl chloride can react with primary and also with secondary amines[1]. |
Cell Assay | Selected mouse brain samples from either cortical or striatal regions (100 mg wet weight) and neuroblastoma cells (SH-SY5Y) pellet derived from 25 cm2 flask are treated with 500 μL of 0.1 M HCl containing 0.2% TDGA, sonicated for 10 min (only for brain tissue), and then centrifuged at 14000 g for 30 min. The supernatant is freeze-dried. 50 μL of reaction buffer and 100 μL of 15 mM Dabsyl chloride are added to the tube and derivatized. |
References |
Density | 1.29 g/cm3 |
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Boiling Point | 483.6ºC at 760 mmHg |
Melting Point | 185 °C (dec.)(lit.) |
Molecular Formula | C14H14ClN3O2S |
Molecular Weight | 323.79800 |
Flash Point | 246.3ºC |
Exact Mass | 323.05000 |
PSA | 70.48000 |
LogP | 5.17630 |
Index of Refraction | 1.607 |
Storage condition | −20°C |
Water Solubility | DMF: soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
|
Symbol |
GHS05 |
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Signal Word | Danger |
Hazard Statements | H314 |
Precautionary Statements | P280-P305 + P351 + P338-P310 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | C |
Risk Phrases | R22;R34 |
Safety Phrases | S26-S36/37/39-S45-S27 |
RIDADR | UN 3261 8/PG 2 |
WGK Germany | 3 |
RTECS | DB8927800 |
Packaging Group | II |
Hazard Class | 8 |
HS Code | 2927000090 |
HS Code | 2927000090 |
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Summary | 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |