15588-23-5

15588-23-5 structure
15588-23-5 structure
  • Name: (2H3)Hydroxylamine (2H)hydrochloride (1:1)
  • Chemical Name: Hydroxylamine-d3 deuteriochloride
  • CAS Number: 15588-23-5
  • Molecular Formula: ClD4NO
  • Molecular Weight: 73.516
  • Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
  • Create Date: 2018-09-14 15:20:03
  • Modify Date: 2024-01-03 16:13:00
  • Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride[1]. Hydroxyamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxyamine hydrochloride is an intermediate of organic synthesis[2].

Name Hydroxylamine-d3 deuteriochloride
Synonyms (H)Hydroxylamine (H)hydrochloride (1:1)
hydroxylamine hydrochloride-d4
Hydroxylamine-d, hydrochloride-d (1:1)
Description Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride[1]. Hydroxyamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxyamine hydrochloride is an intermediate of organic synthesis[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Roh JH, et al. Purification, characterization, and crystallization of monoamine oxidase from Escherichia coli K-12. Biosci Biotechnol Biochem. 1994 Sep;58(9):1652-6.  

Melting Point 156-158ºC(lit.)
Molecular Formula ClD4NO
Molecular Weight 73.516
Exact Mass 73.023247
PSA 46.25000
LogP 0.83660
Symbol GHS05 GHS07 GHS08 GHS09
GHS05, GHS07, GHS08, GHS09
Signal Word Warning
Hazard Statements H290-H302-H312-H315-H317-H319-H351-H373-H400
Precautionary Statements P273-P280-P305 + P351 + P338
Hazard Codes T: Toxic;
Risk Phrases R5
Safety Phrases 22-24-26-37-45-61
RIDADR UN 2923 8/PG 2