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500-05-0

500-05-0 structure
500-05-0 structure
  • Name: 2-Oxo-2H-pyran-5-carboxylic acid
  • Chemical Name: Coumalic acid
  • CAS Number: 500-05-0
  • Molecular Formula: C6H4O4
  • Molecular Weight: 140.094
  • Catalog: Chemical reagent Organic reagent Aromatic acid
  • Create Date: 2018-07-04 08:40:41
  • Modify Date: 2024-01-04 17:17:03
  • Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity[1].

Name Coumalic acid
Synonyms 2-Pyrone-5-carboxylic acid,2-Oxo-2H-pyran-5-carboxylic acid
2H-Pyran-5-carboxylic acid, 2-oxo-
6-oxopyran-3-carboxylic acid
α-Pyrone-5-carboxylic Acid
2-Oxo-2H-pyran-5-carboxylic acid
Cumalic Acid
Coumalic Acid
EINECS 207-899-0
MFCD00006644
Description Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity[1].
Related Catalog
References

[1]. Smith LK, et, al. Flow synthesis of coumalic acid and its derivatization. Department of Chemistry. 2018, 3: 722-732.

Density 1.5±0.1 g/cm3
Boiling Point 282.4±0.0 °C at 760 mmHg
Melting Point 203-205 °C (dec.)(lit.)
Molecular Formula C6H4O4
Molecular Weight 140.094
Flash Point 137.3±19.4 °C
Exact Mass 140.010956
PSA 67.51000
LogP -0.43
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.577
Hazard Codes Xi
Safety Phrases S22-S24/25
WGK Germany 3

~82%

500-05-0 structure

500-05-0

Literature: Rosenmund, Peter; Casutt, Michael; Wittich, Michael Liebigs Annalen der Chemie, 1990 , p. 233 - 238

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500-05-0 structure

500-05-0

Literature: Caldwell et al. Journal of the American Chemical Society, 1944 , vol. 66, p. 1479,1482

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500-05-0 structure

500-05-0

Literature: v. Pechmann Justus Liebigs Annalen der Chemie, 1893 , vol. 273, p. 176

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500-05-0 structure

500-05-0

Literature: v.Pechmann Chemische Berichte, 1884 , vol. 17, p. 936 Justus Liebigs Annalen der Chemie, 1891 , vol. 264, p. 262,272

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500-05-0 structure

500-05-0

Literature: v.Pechmann Chemische Berichte, 1884 , vol. 17, p. 936 Justus Liebigs Annalen der Chemie, 1891 , vol. 264, p. 262,272