Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2
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Purity: 98.0%
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860790-38-1

860790-38-1 structure

Name: M617 TFA
Chemical Name: m617
CAS Number: 860790-38-1
Molecular Formula: C₁₁₂H₁₆₁N₂₉O₂₈
Molecular Weight: 2361.65000
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-04-15 04:36:09
Modify Date: 2024-01-07 12:05:42
M617 is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats[1][2].

Name	m617
Synonyms	GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2 EMDT oxalate

Description	M617 is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Lundström, L., et al. A Galanin Receptor Subtype 1 Specific Agonist. Int J Pept Res Ther 11, 17–27 (2005). [2]. Fang P, et al. Central injection of GalR1 agonist M617 facilitates GLUT4 expression in cardiac muscle of type 2 diabetic rats. Exp Gerontol. 2015;65:85-89.