908844-75-7

908844-75-7 structure

Name: M871
Chemical Name: m871
CAS Number: 908844-75-7
Molecular Formula: C₁₀₈H₁₆₃N₂₇O₂₈
Molecular Weight: 2287.61
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2017-10-09 18:02:58
Modify Date: 2024-04-02 19:05:54
M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM and 420 nM for GalR2 and GalR1, respectively. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain)[1].

Name	m871
Synonyms	trp-thr-leu-asn-ser-ala-gly-tyr-leu-leu-gly-pro-glu-his-pro-pro-pro-ala-leu-ala-leu-ala-nh2

Description	M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM and 420 nM for GalR2 and GalR1, respectively. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	GalR2[1].
References	[1]. U. E. Sollenberg, et al. M871—A Novel Peptide Antagonist Selectively Recognizing the Galanin Receptor Type 2. Int J Pept Res Ther. 2006;12:2965-2982.