937807-66-4

937807-66-4 structure

Name: Neurodazine
Chemical Name: 2-[5-(3-chlorophenyl)furan-2-yl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
CAS Number: 937807-66-4
Molecular Formula: C₂₇H₂₁ClN₂O₃
Molecular Weight: 460.952
Catalog: Signaling Pathways Stem Cell/Wnt Hedgehog
Create Date: 2017-11-27 12:18:04
Modify Date: 2024-01-02 22:20:55
Neurodazine is an imidazole-based small molecule, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. Neurodazine selectively suppresses astrocyte differentiation of P19 cells[1][2].

Name	2-[5-(3-chlorophenyl)furan-2-yl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
Synonyms	1H-Imidazole, 2-[5-(3-chlorophenyl)tetrahydro-2-furanyl]-4,5-bis(4-methoxyphenyl)- Neurodazine 2-[5-(3-Chlorophenyl)tetrahydro-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

Description	Neurodazine is an imidazole-based small molecule, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. Neurodazine selectively suppresses astrocyte differentiation of P19 cells[1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> Hedgehog Signaling Pathways >> Stem Cell/Wnt >> Wnt
References	[1]. Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. [2]. Halder D, et al. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37.

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H318-H413
Precautionary Statements	P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
RIDADR	UN 2811 6.1 / PGIII