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4651-67-6

4651-67-6 structure
4651-67-6 structure
  • Name: 7-Ketolithocholic acid
  • Chemical Name: 7-oxolithocholic acid
  • CAS Number: 4651-67-6
  • Molecular Formula: C24H38O4
  • Molecular Weight: 390.556
  • Catalog: API Digestive system medication Biliary medicine
  • Create Date: 2018-08-30 17:28:42
  • Modify Date: 2024-01-02 00:45:40
  • 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion[1][2].

Name 7-oxolithocholic acid
Synonyms 3-Hydroxy-7-oxocholan-24-oic acid
3α-Hydroxy-7-keto-5β-cholanic Acid
EINECS 225-083-2
3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
4-(3-Hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
3α-Hydroxy-7-oxo-5β-cholanic Acid
Cholan-24-oic acid, 3-hydroxy-7-oxo-
3a-Hydroxy-7-oxo-5b-cholanic acid
Description 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Bile acids are main components of mammalian bile. They are steroid carboxylic acids that synthesized from cholesterol in liver tissue[1].
References

[1]. Choucair I, et al. Quantification of bile acids: a mass spectrometry platform for studying gut microbe connectionto metabolic diseases. J Lipid Res. 2020 Feb;61(2):159-177.

[2]. Salen G, et al. Effect of 7-ketolithocholic acid on bile acid metabolism in humans. Gastroenterology. 1982 Aug;83(2):341-7.

Density 1.1±0.1 g/cm3
Boiling Point 545.9±25.0 °C at 760 mmHg
Melting Point 205ºC
Molecular Formula C24H38O4
Molecular Weight 390.556
Flash Point 298.0±19.7 °C
Exact Mass 390.277008
PSA 74.60000
LogP 4.25
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.535
Hazard Codes Xi
Safety Phrases 22-24/25
HS Code 2918990090
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%