Digestive system medication

There are many diseases in the digestive system, and the medication is complicated and diverse. For esophageal diseases such as reflux esophagitis, antacids, especially cimetidine (Taiweimei), are used. H2 receptor blocker has the effect of neutralizing gastric acid to inhibit gastric acid secretion and reducing irritation. In recent years, the discovery of metoclopramide (morphine) on enhancing the tension of lower esophageal sphincter (LES) has made this choice. The prognosis of the disease has changed. Peptic ulcer and chronic gastritis are common diseases and frequently-occurring diseases of the digestive system. There are many therapeutic drugs. So far, there is no specific treatment. The treatment of antacids and gastric acid is still widely used. That is, the commonly used sodium hydrogencarbonate, calcium strontium magnesium, etc. have gradually been eliminated. Nowadays, aluminum hydroxide is commonly used. This medicine is taken 1 to 2 hours after a meal and can neutralize gastric acid for up to 3 hours. The combination with anticholinergic drugs can both relieve phlegm and relieve pain, and inhibit gastric acid secretion in the evening, which is beneficial to the treatment of peptic ulcer. After the 1950s and 1960s, the commonly used anticholinergic drugs were the introduction of H2 receptor blockers in the late 1970s, and the efficacy of peptic ulcers was significantly improved. With the progress of research, Ranitidine, Famotidine and other new generations of anti-acid effects are stronger, and the clinical application of H2 blockers with reduced side effects can be eliminated. Fast, good effect of increased ulcer healing rate. It is worth mentioning that the proton pump inhibitor omeprazole, Omeprazole, Losec, has strong acid suppression, increases gastric mucosal blood flow, strengthens the gastric mucosal barrier, and treats the disease. Play a more active and effective role. At present, although the treatment of chronic gastritis is not satisfactory, the application of aluminum hydroxide, sucralfate to adsorb bile salts, and to protect the gastric mucosal barrier and use morphine for bile reflux gastritis has a good effect. In recent years, it has been found that duodenal bulb ulcers are almost always associated with antral sinusitis, and more than 80% of them have inflammatory lesions caused by Helicobacter pylori (HP). Therefore, the application of some corresponding antibiotics at the same time plays a good role in promoting ulcer healing, reducing recurrence, eliminating inflammation, and improving the efficacy of peptic ulcer and chronic gastritis. Citric acid colloidal sputum (De-No1, Dele) can stimulate mucus secretion, protect the gastric mucosal barrier, and also have a certain killing effect on HP. If it can be properly selected according to the condition, the rational use of the above drugs can play a more effective role in improving the efficacy of peptic ulcer, chronic gastritis and improving the prognosis. Pepsin and other digestive drugs are known to have limited efficacy. Insufficient dyspepsia such as protein, starch and fat caused by chronic pancreatitis, trypsin preparation (pancreatin tablets, multi-enzyme tablets) is still used, generally requires a larger dose to be effective. There are not many domestic preparations for the treatment of constipation. The commonly used laxatives are magnesium milk, phenolphthalein, liquid paraffin and the like. About the antidiarrheal agent Opioid preparations are rarely used domestically. Commonly used are aluminum hydroxide gel, phenethylpiperidine. It is worth pointing out that the latter has a similar effect to meperidine, which is commonly used for addiction, so it is not suitable for long-term application. Lactulose is a special disaccharide that is not digested. It can be broken down into lactose and acetic acid by bacteria in the large intestine, which acts as a permeable laxative. The acidified feces can inhibit the production of ammonia by the intestinal bacteria and cause the blood ammonia to diffuse into the colon cavity, so it has a blood-lowering effect and has a certain therapeutic effect on hepatic coma.