Name | scopolamine methobromide |
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Synonyms |
Epoxymethamine bromide
Nutrop Methylscopolamine bromide (1R,2R,4S,5S,7s)-7-{[(2S)-3-Hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0]nonane bromide N-Methylscopolamine Bromide UNII-RTN51LK7WL 3-Oxa-9-azoniatricyclo[3.3.1.0]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide, (1R,2R,4S,5S)- (1:1) (-)-Tropic acid Ester with 6b,7b-Epoxy-3a-hydroxy-8-methyl-1aH,5aH-tropanium Bromide (-)-Scopolamine Methobromide 3-oxa-9-azoniatricyclo[3.3.1.0]nonane, 7-[[(2S)-3-hydroxy-1-oxo-2-phenylpropyl]oxy]-9,9-dimethyl-, bromide, (1R,2R,4S,5S)- Neo-avagal N-Methylhyoscine bromide N-methyl scopolammonium bromide Scopolamine methobromide Methscopolamine (bromide) Restropin Scopolamin methylbromide scopolamine methylbromide Holopan (−)-Scopolamine methyl bromide Hyoscine methyl bromide Methscopolamine bromide 6b,7b-Epoxy-3a-hydroxy-8-methyl-1aH,5aH-tropanium Bromide Paraspan EINECS 205-844-5 Lescopine bromide (-)-N-methylscopolamine bromide [7(S)-(1a,2b,4b,5a,7b)]-7-(3-Hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide Methylbromide Scopolamine Pamine Pamine Bromide Methscopolamine Bromide Blocan N-Methylscopolammonium bromide (1a,2b,4b,5a,7b)-7-[(2S)-3-Hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide Methscopolamine methylbromide MFCD00078560 Diopal Holopon Hyoscine methyl bromide Proscomide Mescopil (−)-Scopolamine methyl bromide Hyoscine methyl bromide Methscopolamine bromide Scopolamine Methyl Bromide Ampyrox Methscopolamine Oxitropium bromide impurity B |
Description | Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker. Target: mAChRMethylscopolamine is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. With the advent of proton pump inhibitors and antihistamine medications it is rarely used for this. It can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. From Wikipedia.Methscopolamine (Pamine), an anti-acetylcholine drug, prevented ulcer formation, reduced further volume and acid output but produced a 3-4 fold increase in hexosamine concentration. Tissue (corpus and antrum) hexosamine was moderately reduced by restraint. In the corpus, this was counteracted by methscopolamine but antrum hexosamine was not influenced by this drug. The anti-ulcer property of methscopolamine may be due not only to its effect on acid secretion but also to the rise in gastric mucus concentration that it produced [1]. |
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Related Catalog | |
References |
Molecular Formula | C18H24BrNO4 |
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Molecular Weight | 398.292 |
Exact Mass | 397.088867 |
PSA | 59.06000 |
Index of Refraction | -24 ° (C=1, H2O) |
Water Solubility | H2O: 50 mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS07, GHS09 |
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Signal Word | Warning |
Hazard Statements | H312 + H332-H400 |
Precautionary Statements | P261-P280 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | T,N |
Risk Phrases | 23/24/25-50/53-20/21/22 |
Safety Phrases | 36/37/39-45-61-60-36/37 |
RIDADR | UN 1544 6.1/PG 3 |
WGK Germany | 3 |
RTECS | YM3675000 |
Packaging Group | III |
HS Code | 2934999090 |
Precursor 1 | |
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DownStream 0 |
HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |