15579-00-7

15579-00-7 structure

Name: Aminoethyl-SS-propionic acid
Chemical Name: 3-(2-aminoethyldisulfanyl)propanoic acid
CAS Number: 15579-00-7
Molecular Formula: C₅H₁₁NO₂S₂
Molecular Weight: 181.27600
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-10-27 01:22:04
Modify Date: 2024-01-09 22:03:04
Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	3-(2-aminoethyldisulfanyl)propanoic acid
Synonyms	MFCD07357249

Description	Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Hazard Codes	Xn

156-57-0

107-96-0

51-85-4

1119-62-6

Detail

Literature: Tetrahedron, , vol. 52, # 15 p. 5591 - 5606

40302-08-7

73891-30-2

15579-00-7

1849-36-1

Literature: Journal of Organic Chemistry, , vol. 45, # 15 p. 3100 - 3103

2365-49-3

73873-04-8

15579-00-7

1849-36-1

Literature: Journal of Organic Chemistry, , vol. 45, # 15 p. 3100 - 3103

71899-86-0

107-96-0

15139-21-6

15579-00-7

Literature: Bioorganic Chemistry, , vol. 26, # 6 p. 356 - 364