Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Benzetimide hydrochloride
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Benzetimide HCl
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Tony Cao

5633-14-7

5633-14-7 structure

5633-14-7 structure

Name: Benzetimide hydrochloride
Chemical Name: 3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride
CAS Number: 5633-14-7
Molecular Formula: C₂₃H₂₇ClN₂O₂
Molecular Weight: 398.926
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2018-10-01 10:21:14
Modify Date: 2024-01-04 00:02:15
Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist. Target: mAChR

Name	3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride
Synonyms	Dioxatrine 1'-Benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione hydrochloride (1:1) Spasmentral R 4929 Benzetimide HCl EINECS 227-072-8 [3,4'-Bipiperidine]-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, hydrochloride (1:1) McN-JR4929 BENZETIMIDE HYDROCHLORIDE Benzetimide (hydrochloride)

Description	Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist. Target: mAChR
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Neurological Disease

Boiling Point	543.9ºC at 760 mmHg
Molecular Formula	C₂₃H₂₇ClN₂O₂
Molecular Weight	398.926
Flash Point	282.7ºC
Exact Mass	398.176117
PSA	52.90000
LogP	4.28900
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA4030000

CHEMICAL NAME :: Glutarimide, 2-(1-benzyl-4-piperidyl)-2-phenyl-, hydrochloride

CAS REGISTRY NUMBER :: 5633-14-7

LAST UPDATED :: 199707

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H26-N2-O2.Cl-H

MOLECULAR WEIGHT :: 398.97

WISWESSER LINE NOTATION :: T6VMVTJ DR& D- DT6NTJ A1R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37600 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1365,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 680 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,283,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 46 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1365,1971

Hazard Codes	Xn
Risk Phrases	22
RIDADR	UN 3249
Packaging Group	III
Hazard Class	6.1(b)