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82-88-2

82-88-2 structure
82-88-2 structure

Name 2-methyl-9-phenyl-1,3,4,9-tetrahydroindeno[2,1-c]pyridine
Synonyms Fenindamina
Phenindamine (INN)
Phenindamine [INN:BAN]
Phenindaminum
2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridine
Nolahist
2-Methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin
Phenindiamine
Phenindamin
Phenindaminum [INN-Latin]
Fenindamina [INN-Spanish]
Thephorin
Phenindamine
Description Phenindamine (Nu 1504) is an antihistamine[1].
Related Catalog
In Vivo Phenindamine (2-10 mg/kg; i.p.; once) shows performance enhancement effect in rats[1]. Animal Model: Adult male Long-Evans strain rats[1] Dosage: 2, 5 and 10 mg/kg Administration: Intraperitoneal injection, once Result: Decreased attention index (AI) and increase the AI variance. Produced a dose-related increase in the performance index (PI).
Density 1.15g/cm3
Boiling Point 416.5ºC at 760 mmHg
Melting Point 90-91°
Molecular Formula C19H19N
Molecular Weight 261.36100
Flash Point 183ºC
Exact Mass 261.15200
PSA 3.24000
LogP 3.85910
Index of Refraction 1.652

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK9460500
CHEMICAL NAME :
1H-Indeno(2,1-c)pyridine, 2,3,4,9-tetrahydro-2-methyl-9-phenyl-
CAS REGISTRY NUMBER :
82-88-2
BEILSTEIN REFERENCE NO. :
0221083
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H19-N

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
129 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 124,350,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
265 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,271,1970

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82-88-2 structure

82-88-2

Literature: Hoffmann-La Roche Patent: DE820141 , 1951 ; Full Text Show Details Hoffmann-La Roche Patent: US2470108 , 1947 ; DRP/DRBP Org.Chem. Full Text Show Details Plati; Wenner Journal of Organic Chemistry, 1955 , vol. 20, p. 1412,1422

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82-88-2 structure

82-88-2

Literature: Plati; Wenner Journal of Organic Chemistry, 1955 , vol. 20, p. 1412,1422

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82-88-2 structure

82-88-2

Literature: Plati; Wenner Journal of Organic Chemistry, 1955 , vol. 20, p. 1412,1422
Precursor  3

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