125291-15-8

125291-15-8 structure
125291-15-8 structure
  • Name: 3’-Deoxy-3’-fluoro-xyloguanosine
  • Chemical Name: 2-amino-9-[(2R,3S,4R,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
  • CAS Number: 125291-15-8
  • Molecular Formula: C10H12FN5O4
  • Molecular Weight: 285.23
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-01-10 18:50:02
  • Modify Date: 2024-01-10 09:19:46
  • 3’-Deoxy-3’-fluoro-xyloguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 2-amino-9-[(2R,3S,4R,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonyms dF.b.XG
Description 3’-Deoxy-3’-fluoro-xyloguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 2.17g/cm3
Boiling Point 726.1ºC at 760mmHg
Molecular Formula C10H12FN5O4
Molecular Weight 285.23
Flash Point 392.9ºC
Exact Mass 285.08700
PSA 140.27000
Vapour Pressure 3.94E-22mmHg at 25°C
Index of Refraction 1.876