1313874-96-2

1313874-96-2 structure
1313874-96-2 structure
  • Name: Afatinib-d6
  • Chemical Name: Afatinib D6
  • CAS Number: 1313874-96-2
  • Molecular Formula: C24H19D6ClFN5O3
  • Molecular Weight: 491.97500
  • Catalog: Research Areas Cancer
  • Create Date: 2018-04-07 08:00:00
  • Modify Date: 2024-01-11 20:24:23
  • Afatinib D6 (BIBW 2992 D6) is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor[1].

Name Afatinib D6
Synonyms (S,E)-4-(bis(trideuteromethyl)amino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
Description Afatinib D6 (BIBW 2992 D6) is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor[1].
Related Catalog
Target

EGFR[1]

References

[1]. Li D, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008 Aug 7;27(34):4702-11.

Molecular Formula C24H19D6ClFN5O3
Molecular Weight 491.97500
Exact Mass 491.20100
PSA 88.61000
LogP 4.53590
Storage condition -20C