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94356-22-6

94356-22-6 structure
94356-22-6 structure
  • Name: Rhapontigenin 3'-O-glucoside
  • Chemical Name: rhapontigenin 3'-O-β-D-glucopyranoside
  • CAS Number: 94356-22-6
  • Molecular Formula: C21H24O9
  • Molecular Weight: 420.410
  • Catalog: Research Areas Cancer
  • Create Date: 2018-07-25 11:32:38
  • Modify Date: 2024-01-08 12:52:20
  • Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent[1].

Name rhapontigenin 3'-O-β-D-glucopyranoside
Synonyms Rhapontigenin 3'-O-glucoside
5-[(E)-2-(3,5-Dihydroxyphenyl)vinyl]-2-methoxyphenyl β-D-glucopyranoside
β-D-Glucopyranoside, 5-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]-2-methoxyphenyl
Rhapontigenin 3'-O-glucopyranoside
Description Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent[1].
Related Catalog
In Vitro Rhapontigenin exhibits a potent and selective inhibition of human P450 1A1 with an IC50 of 0.4 μM. Rhapontigenin shows 400-fold selectivity for P450 1A1 over P450 1A2 and 23-fold selectivity for P450 1A1 over P450 1B1[1].
References

[1]. Chun YJ, et al. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin. Drug Metab Dispos. 2001 Apr;29(4 Pt 1):389-93.

Density 1.5±0.0 g/cm3
Boiling Point 711.3±0.0 °C at 760 mmHg
Molecular Formula C21H24O9
Molecular Weight 420.410
Flash Point 384.0±0.0 °C
Exact Mass 420.142029
PSA 149.07000
LogP -0.03
Vapour Pressure 0.0±0.0 mmHg at 25°C
Index of Refraction 1.711
Precursor  0

DownStream  2