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35536-53-9

35536-53-9 structure
35536-53-9 structure
  • Name: 11-deoxy Prostaglandin E2
  • Chemical Name: 7-[(1R,2R)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
  • CAS Number: 35536-53-9
  • Molecular Formula: C20H32O4
  • Molecular Weight: 336.47
  • Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
  • Create Date: 2016-06-14 15:12:54
  • Modify Date: 2024-01-14 20:15:03
  • 11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions[1][2].

Name 7-[(1R,2R)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
Synonyms 11-Deoxy-PGE2
(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,13-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S)-
Description 11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions[1][2].
Related Catalog
References

[1]. Holt MC, et al. Improved homology modeling of the human & rat EP4 prostanoid receptors. BMC Mol Cell Biol. 2019 Aug 27;20(1):37.  

[2]. Ungrin MD, et al. Key structural features of prostaglandin E(2) and prostanoid analogs involved in binding and activation of the human EP(1) prostanoid receptor. Mol Pharmacol. 2001 Jun;59(6):1446-56.  

Density 1.1±0.1 g/cm3
Boiling Point 510.3±45.0 °C at 760 mmHg
Molecular Formula C20H32O4
Molecular Weight 336.47
Flash Point 276.5±25.2 °C
Exact Mass 336.230072
PSA 74.60000
LogP 3.41
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.543