- BioBioPha
- China
- Product Name: Humantenmine
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Humantenmine
- Price: ￥4800.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
82354-38-9
82354-38-9 structure
- Name: Humantenmine
- Chemical Name: Humantenmine
- CAS Number: 82354-38-9
- Molecular Formula: C19H22N2O3
- Molecular Weight: 326.390
- Catalog: Natural product Alkaloid
- Create Date: 2018-10-17 10:19:45
- Modify Date: 2024-01-12 16:20:53
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Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2].
| Name | Humantenmine |
|---|---|
| Synonyms |
(3S,3'R,3a'S,6'R,8a'S)-2'-ethyl-1-methoxy-3a',4',8',8a'-tetrahydro-3'H,6'H-spiro[indole-3,7'-[3,6]methanooxepino[4,3-b]pyrrol]-2(1H)-one
Gelsedine, 4,20-didehydro- (1'R,3S,4'S,7'R,8'S)-6'-Ethyl-1-methoxyspiro[indole-3,2'-[10]oxa[5]azatricyclo[5.3.1.0]undec[5]en]-2(1H)-one |
| Description | Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Humantenmine (HMT) decreases the 14-day survival rate of the mice to 17% after they are intragastrically treated with HMT, along with hepatic injury and increasing alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels. CYP3A4/5 mediates the metabolism and detoxification of HMT[1][2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 463.6±55.0 °C at 760 mmHg |
| Molecular Formula | C19H22N2O3 |
| Molecular Weight | 326.390 |
| Flash Point | 234.2±31.5 °C |
| Exact Mass | 326.163055 |
| PSA | 51.13000 |
| LogP | 3.68 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.712 |
| Hazard Codes | Xi |
|---|