Humantenmine

Modify Date: 2024-01-12 16:20:53

Humantenmine Structure
Humantenmine structure
Common Name Humantenmine
CAS Number 82354-38-9 Molecular Weight 326.390
Density 1.4±0.1 g/cm3 Boiling Point 463.6±55.0 °C at 760 mmHg
Molecular Formula C19H22N2O3 Melting Point N/A
MSDS N/A Flash Point 234.2±31.5 °C

 Use of Humantenmine


Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2].

 Names

Name Humantenmine
Synonym More Synonyms

 Humantenmine Biological Activity

Description Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2].
Related Catalog
In Vitro Humantenmine (HMT) decreases the 14-day survival rate of the mice to 17% after they are intragastrically treated with HMT, along with hepatic injury and increasing alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels. CYP3A4/5 mediates the metabolism and detoxification of HMT[1][2].
References

[1]. Kun Yang, et al. Development and In-House Validation of a Sensitive LC-MS/MS Method for Simultaneous Quantification of Gelsemine, Koumine and Humantenmine in Porcine Plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 15;1076:54-60.

[2]. Rongjin Sun, et al. CYP3A4/5 Mediates the Metabolic Detoxification of Humantenmine, a Highly Toxic Alkaloid From Gelsemium Elegans Benth. J Appl Toxicol. 2019 Sep;39(9):1283-1292.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 463.6±55.0 °C at 760 mmHg
Molecular Formula C19H22N2O3
Molecular Weight 326.390
Flash Point 234.2±31.5 °C
Exact Mass 326.163055
PSA 51.13000
LogP 3.68
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.712

 Safety Information

Hazard Codes Xi

 Synonyms

(3S,3'R,3a'S,6'R,8a'S)-2'-ethyl-1-methoxy-3a',4',8',8a'-tetrahydro-3'H,6'H-spiro[indole-3,7'-[3,6]methanooxepino[4,3-b]pyrrol]-2(1H)-one
Gelsedine, 4,20-didehydro-
(1'R,3S,4'S,7'R,8'S)-6'-Ethyl-1-methoxyspiro[indole-3,2'-[10]oxa[5]azatricyclo[5.3.1.0]undec[5]en]-2(1H)-one
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Humantenmine
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng


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Price: ¥2250/5 mg

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