33018-91-6

33018-91-6 structure
33018-91-6 structure

Name boc-his(tos)-merrifield resin
Synonyms Monoethyl Heptanedioate
BOC-HIS(TOS)-MBHA RESIN
BOC-L-HIS(TOS)-MBHA RESIN
heptanedioic acid monoethyl ester
6-(ethoxycarbonyl)hexanoic acid
PAM BOC-L-HISTIDINE (TOS)
7-ethoxy 7-oxo heptanoic acid
Monoethyl PiMelate
BOC-HIS(TOS)-CMS RESIN
pimelicacidmonethylester
MFCD00801202
Pimelic Acid Monoethyl Ester
BOC-HIS(TOS)-BHA PS RESIN
Ethyl hydrogen pimelate
BOC-HIS(TOS)-BHA RESIN
EINECS 251-346-6
BOC-HIS(TOS)-PAM RESIN
Description Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].
Related Catalog
References

[1]. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.

Density 1.074 g/cm3
Boiling Point 135-138ºC 1mm
Melting Point 10ºC
Molecular Formula C9H16O4
Molecular Weight 188.22100
Flash Point 108ºC
Exact Mass 188.10500
PSA 63.60000
LogP 1.58460
Index of Refraction 1.442
Storage condition 2-8°C
Water Solubility Not miscible or difficult to mix with water.
Risk Phrases R36/38
Safety Phrases S26-S36
WGK Germany 3
HS Code 2918990090
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%