305366-98-7

305366-98-7 structure

Name: GI 181771
Chemical Name: 3-[[(3S)-2,4-dioxo-1-[2-oxo-2-(N-propan-2-ylanilino)ethyl]-5-phenyl-1,5-benzodiazepin-3-yl]carbamoylamino]benzoic acid
CAS Number: 305366-98-7
Molecular Formula: C₃₄H₃₁N₅O₆
Molecular Weight: 605.64000
Catalog: Signaling Pathways GPCR/G Protein Cholecystokinin Receptor
Create Date: 2017-04-06 06:08:14
Modify Date: 2024-01-09 10:07:36
GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.

Name	3-[[(3S)-2,4-dioxo-1-[2-oxo-2-(N-propan-2-ylanilino)ethyl]-5-phenyl-1,5-benzodiazepin-3-yl]carbamoylamino]benzoic acid
Synonyms	unii-6yf0shr37t GI 181771

Description	GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Cholecystokinin Receptor Research Areas >> Metabolic Disease
Target	Target: Cholecystokinin 1 receptor[1]
References	[1]. Myer JR, et al. Species- and dose-specific pancreatic responses and progression in single- and repeat-dose studies with GI181771X: a novel cholecystokinin 1 receptor agonist in mice, rats, and monkeys. Toxicol Pathol. 2014 Jan;42(1):260-74. [2]. Roses AD, et al. Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake. Clin Pharmacol Ther. 2009 Apr;85(4):362-5.