1215370-26-5

1215370-26-5 structure

Name: Ketopioglitazone-d4
Chemical Name: 5-[[4-[2-(5-acetylpyridin-2-yl)ethoxy]-2,3,5,6-tetradeuteriophenyl]methyl]-1,3-thiazolidine-2,4-dione
CAS Number: 1215370-26-5
Molecular Formula: C₁₉H₁₄D₄N₂O₄S
Molecular Weight: 374.45
Create Date: 2018-06-21 11:22:52
Modify Date: 2024-02-06 14:17:06
Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone.

Name	5-[[4-[2-(5-acetylpyridin-2-yl)ethoxy]-2,3,5,6-tetradeuteriophenyl]methyl]-1,3-thiazolidine-2,4-dione
Synonyms	Keto Pioglitazone-d4 (M-III) Keto-Pioglitazone-Labeled d4 [2H4]-Pioglitazone ketone

Description	Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.