1215370-26-5

1215370-26-5 structure
1215370-26-5 structure
  • Name: Ketopioglitazone-d4
  • Chemical Name: 5-[[4-[2-(5-acetylpyridin-2-yl)ethoxy]-2,3,5,6-tetradeuteriophenyl]methyl]-1,3-thiazolidine-2,4-dione
  • CAS Number: 1215370-26-5
  • Molecular Formula: C19H14D4N2O4S
  • Molecular Weight: 374.45
  • Create Date: 2018-06-21 11:22:52
  • Modify Date: 2024-02-06 14:17:06
  • Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone.

Name 5-[[4-[2-(5-acetylpyridin-2-yl)ethoxy]-2,3,5,6-tetradeuteriophenyl]methyl]-1,3-thiazolidine-2,4-dione
Synonyms Keto Pioglitazone-d4 (M-III)
Keto-Pioglitazone-Labeled d4
[2H4]-Pioglitazone ketone
Description Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Formula C19H14D4N2O4S
Molecular Weight 374.45
Exact Mass 374.12400
PSA 114.15000
LogP 3.07570