129101-54-8
129101-54-8 structure
- Name: Rivastigmine (tartrate)
- Chemical Name: rivastigmine tartrate
- CAS Number: 129101-54-8
- Molecular Formula: C18H28N2O8
- Molecular Weight: 400.423
- Catalog: API Nervous system medication Brain metabolism regulating drug
- Create Date: 2018-02-17 08:00:00
- Modify Date: 2024-01-02 08:39:53
-
Rivastigmine tartrate, an cholinesterase inhibitor(IC50= 5.5 uM), inhibits both butyrylcholinesterase and acetylcholinesteraseIC50 value: 5.5 uMTarget: AChERivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions. Rivastigmine, a cholinesterase inhibitor, inhibits both butyrylcholinesterase and acetylcholinesterase. It is thought to work by inhibiting these cholinesterase enzymes, which would otherwise break down the brain chemical acetylcholine.
| Name | rivastigmine tartrate |
|---|---|
| Synonyms |
3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (1:1)
acide (2R,3R)-2,3-dihydroxybutanedioïque - éthyl(méthyl)carbamate de 3-[(1S)-1-(diméthylamino)éthyl]phényle (1:1) RivastigMine L-Tartrate Rivastigmine Tartrate Salt N-Ethyl-N-methylcarbamic Acid 3-[(S)-1-(Dimethylamino)ethyl]phenyl Ester L-Tartrate Rivastigmine (2R,3R)-2,3-Dihydroxysuccinic acid - 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate (1:1) (S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxysuccinate Rivastigmine Tartrate 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (salt) (2R,3R)-2,3-Dihydroxybutandisäure--3-[(1S)-1-(dimethylamino)ethyl]phenyl-ethyl(methyl)carbamat(1:1) 3-[(S)-1-(Dimethylamino)ethyl]phenyl N-Ethyl-N-methylcarbamate L-Tartrate Rivastigmine hydrogen tartrate Rivastigmine (tartrate) |
| Description | Rivastigmine tartrate, an cholinesterase inhibitor(IC50= 5.5 uM), inhibits both butyrylcholinesterase and acetylcholinesteraseIC50 value: 5.5 uMTarget: AChERivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions. Rivastigmine, a cholinesterase inhibitor, inhibits both butyrylcholinesterase and acetylcholinesterase. It is thought to work by inhibiting these cholinesterase enzymes, which would otherwise break down the brain chemical acetylcholine. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 316.2ºC at 760 mmHg |
|---|---|
| Melting Point | 123-1250C |
| Molecular Formula | C18H28N2O8 |
| Molecular Weight | 400.423 |
| Flash Point | 145ºC |
| Exact Mass | 400.184570 |
| PSA | 147.84000 |
| LogP | 0.63710 |
| Vapour Pressure | 0.000416mmHg at 25°C |
| Storage condition | -20°C Freezer |
| HS Code | 2942000000 |
|---|