173170-12-2

173170-12-2 structure

Name: 5'-Protected 2,2'-anhydrouridine
Chemical Name: 5'-DMTr-2,2'-anhydrouridine
CAS Number: 173170-12-2
Molecular Formula: C₃₀H₂₈N₂O₇
Molecular Weight: 528.55
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-08-14 01:29:39
Modify Date: 2024-01-12 16:24:16
5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5'-DMTr-2,2'-anhydrouridine
Synonyms	5'-O-(4,4'-dimethoxytrityl)-2,2'-O-anhydro-1-(β-D-arabinofuranosyl)uracil 2,2'-anhydro-5'-O-(4,4'-dimethoxytrityl)uridine 2,2'-O-anhydro-5'-O-(4,4'-dimethoxytrityl)(β-D-arabinofuranosyl)uracil 2,2'-O-anhydro-1-[5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl]uracil 5'-O-(4,4'-dimethoxytrityl)-2,2'-anhydrouridine 5'-O-dimethoxytrityl anhydrouridine

Description	5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.