124387-19-5

124387-19-5 structure

Name: 5(6)-Carboxyfluorescein Diacetate
Chemical Name: 5(6)-Carboxyfluorescein diacetate
CAS Number: 124387-19-5
Molecular Formula: C₂₅H₁₆O₉
Molecular Weight: 460.39
Catalog: Dye Reagents
Create Date: 2018-06-12 09:09:51
Modify Date: 2024-01-02 04:17:12
5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.

Name	5(6)-Carboxyfluorescein diacetate
Synonyms	3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-4-carboxylic acid,3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid 5(6)-Carboxy-di-O-acetylfluorescein 3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid - 3',6'-diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-7-carboxylic acid (1:1) Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, compd. with 3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-7-carboxylic acid (1:1) 5(6)-CFDA

Description	5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
References	[1]. Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218(4):548-53. [2]. Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105(1):221-9. [3]. Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19(9):1283-6.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
RIDADR	NONH for all modes of transport