Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-Nitrothiazol-2-amine
Price: ￥198.0/100g ￥408.0/500g
Purity: 97.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Amino-5-nitrothiazole suppliers in China
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Amino-5-nitrothiazole
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

121-66-4

121-66-4 structure

Name: 5-Nitrothiazol-2-amine
Chemical Name: 2-Amino-5-nitrothiazole
CAS Number: 121-66-4
Molecular Formula: C₃H₃N₃O₂S
Molecular Weight: 145.140
Catalog: Pharmaceutical intermediate Heterocyclic compound Thiophene compound
Create Date: 2018-07-14 21:40:25
Modify Date: 2024-01-02 20:34:12

Name	2-Amino-5-nitrothiazole
Synonyms	2-Amino-5-nitrothiazole 2-Thiazolamine, 5-nitro- 5-nitro-2-thiazolylamin 5-Nitrothiazol-2-amine 5-Nitro-1,3-thiazol-2-amine MFCD00005326 EINECS 204-490-9 2-AMINO-5-NITRO THIAZOLE

Density	1.7±0.1 g/cm3
Boiling Point	345.1±15.0 °C at 760 mmHg
Melting Point	195-200 °C (dec.)(lit.)
Molecular Formula	C₃H₃N₃O₂S
Molecular Weight	145.140
Flash Point	162.5±20.4 °C
Exact Mass	144.994598
PSA	112.97000
LogP	0.83
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.705
Stability	Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.
Water Solubility	<0.1 g/100 mL at 20 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ2800000

CHEMICAL NAME :: Thiazole, 2-amino-5-nitro-

CAS REGISTRY NUMBER :: 121-66-4

BEILSTEIN REFERENCE NO. :: 0126797

LAST UPDATED :: 199710

DATA ITEMS CITED :: 24

MOLECULAR FORMULA :: C3-H3-N3-O2-S

MOLECULAR WEIGHT :: 145.15

WISWESSER LINE NOTATION :: T5N CSJ BZ DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia Blood - lymphoma, including Hodgkin's disease

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 23 gm/kg/46W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - uterine tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 600 mg/kg

SEX/DURATION :: male 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 700 mg/kg

SEX/DURATION :: male 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 15600 ug/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),103,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,71,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,71,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R20/21/22;R40
Safety Phrases	S26-S45-S24/25
RIDADR	2811
WGK Germany	3
RTECS	XJ2800000
HS Code	2934100090

96-50-4

121-66-4

Literature: Proceedings - Indian Academy of Sciences, Section A, , # 22 p. 362,376 Galenica Acta, , vol. 12, p. 249,252 Journal of Organic Chemistry, , vol. 20, p. 499,505

59024-01-0

121-66-4

Literature: Canadian Journal of Chemistry, , vol. 34, p. 1261,1267

140-40-9

121-66-4

Literature: Proceedings - Indian Academy of Sciences, Section A, , # 22 p. 362,376 Yakugaku Zasshi, , vol. 72, p. 1020 Chem.Abstr., , p. 10286

2719-23-5

121-66-4

Literature: US2617809 , ;

96-50-4

625-58-1

121-66-4

Literature: Annali di Chimica Applicata, , vol. 38, p. 449,454

73430-27-0

17356-08-0

121-66-4

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 24 p. 7414 - 7417

Precursor 6
96-50-4 59024-01-0 140-40-9 2719-23-5
625-58-1 73430-27-0
DownStream 10
14538-17-1 19783-57-4 3034-47-7 3034-48-8
55981-09-4 16060-67-6 326-05-6 349121-09-1
3311-98-6 14527-46-9

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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