Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Nithiamide
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Nithiamide
Price: ￥518.0/1g ￥1868.0/5g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Acetamide,N-(5-nitro-2-thiazolyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

140-40-9

140-40-9 structure

Name: Nithiamide
Chemical Name: 2-Acetamido-5-nitrothiazole
CAS Number: 140-40-9
Molecular Formula: C₅H₅N₃O₃S
Molecular Weight: 187.17600
Catalog: analytical chemistry Standard Analytical standard
Create Date: 2018-08-23 10:30:31
Modify Date: 2024-01-02 14:48:41
Nithiamide is a non-5-nitroimidazole drugs, is a antibiotic used in veterinary.

Name	2-Acetamido-5-nitrothiazole
Synonyms	EINECS 205-414-7 MFCD00022438 N-(5-nitro-1,3-thiazol-2-yl)acetamide 2-Acetamido-5-Nitrothiazole N-(5-Nitrothiazol-2-yl)acetamide Nithiamide

Description	Nithiamide is a non-5-nitroimidazole drugs, is a antibiotic used in veterinary.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection

Density	1.598g/cm3
Boiling Point	303.8ºC at 760mmHg
Melting Point	263°C (dec.)
Molecular Formula	C₅H₅N₃O₃S
Molecular Weight	187.17600
Flash Point	137.5ºC
Exact Mass	187.00500
PSA	116.05000
LogP	1.60590
Vapour Pressure	0.000911mmHg at 25°C
Index of Refraction	1.666

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ1570000

CHEMICAL NAME :: Thiazole, 2-acetamido-5-nitro-

CAS REGISTRY NUMBER :: 140-40-9

BEILSTEIN REFERENCE NO. :: 0167361

LAST UPDATED :: 199612

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C5-H5-N3-O3-S

MOLECULAR WEIGHT :: 187.19

WISWESSER LINE NOTATION :: T5N CSJ BMV1 DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Blood - changes in cell count (unspecified) Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - turkey

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Gene conversion and mitotic recombination

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 200 ppm

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,153,1983

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S22-S36/37
RIDADR	NONH for all modes of transport
RTECS	XJ1570000
HS Code	2934100090

121-66-4

108-24-7

~90%

140-40-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 22, # 5 p. 1626 - 1633

2719-23-5

140-40-9

Literature: Proceedings - Indian Academy of Sciences, Section A, , # 22 p. 362,376 Yakugaku Zasshi, , vol. 72, p. 1020 Chem.Abstr., , p. 10286 Galenica Acta, , vol. 12, p. 249,252 Takamine Kenkyusho Nenpo, , vol. 8, p. 40 Chem.Abstr., , p. 359

7336-54-1

140-40-9

Literature: Journal of the American Chemical Society, , vol. 71, p. 4007,4009

121-66-4

140-40-9

Literature: Annali di Chimica Applicata, , vol. 38, p. 449,454

2719-23-5

625-58-1

140-40-9

Literature: Annali di Chimica Applicata, , vol. 38, p. 449,454

108-24-7

57530-25-3

140-40-9

Literature: Pharmaceutical Chemistry Journal, , vol. 9, # 9 p. 584 - 585 Khimiko-Farmatsevticheskii Zhurnal, , vol. 9, # 9 p. 36 - 37

Precursor 6
121-66-4 108-24-7 2719-23-5 7336-54-1
625-58-1 57530-25-3
DownStream 1
121-66-4

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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