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857284-78-7

857284-78-7 structure
857284-78-7 structure
  • Name: m-PEG3-S-Acetyl
  • Chemical Name: tri(ethylene glycol) methyl ether thioacetate
  • CAS Number: 857284-78-7
  • Molecular Formula: C9H18O4S
  • Molecular Weight: 222.30200
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-01-18 10:47:57
  • Modify Date: 2024-01-07 20:51:42
  • m-PEG3-S-Acetyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name tri(ethylene glycol) methyl ether thioacetate
Synonyms (triethyleneglycol)thioacetate
methyltri(oxyethylene) thioacetate
M3OTA
triethylene glycol methyl ether thioacetate
Description m-PEG3-S-Acetyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C9H18O4S
Molecular Weight 222.30200
Exact Mass 222.09300
PSA 70.06000
LogP 0.94570
Precursor  0

DownStream  1