913830-15-6

913830-15-6 structure

Name: NS 9283
Chemical Name: Benzonitrile, 3-[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]-
CAS Number: 913830-15-6
Molecular Formula: C₁₄H₈N₄O
Molecular Weight: 248.24000
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2017-06-27 05:20:00
Modify Date: 2024-01-12 12:59:54
NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson's disease and Alzheimer's disease[1].

Name	Benzonitrile, 3-[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]-
Synonyms	3-[3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl]benzonitrile NS 9283

Description	NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson's disease and Alzheimer's disease[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. M Grupe, et al. Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)₃(β2) ₂nicotinic ACh receptors. Br J Pharmacol. 2013 Apr;168(8):2000-10.