Name | 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid |
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Synonyms |
D-Alaninamide, N-(4-aminobenzoyl)glycyl-L-prolyl-D-leucyl-N-hydroxy-
1-[2-[(4-aminobenzoyl)amino]acetyl]-N-[1-[[1-(hydroxyamino)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide MFCD00237459 N-(4-Aminobenzoyl)glycyl-L-prolyl-D-leucyl-N-hydroxy-D-alaninamide |
Description | FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2]. |
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Related Catalog | |
In Vitro | FN-439 inhibits collagenase-1 with an IC50 value of 1 μM[1]. FN-439 (1 μM) reduces the invasive potential of MDA-MB-231 breast cancer cells[1]. |
In Vivo | FN-439 significantly decreases neutrophils and macrophages, shows extensive bone formation and active cementogenesis in the periapical region when has a combination with ofloxaci[2]. |
Density | 1.3±0.1 g/cm3 |
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Molecular Formula | C23H34N6O6 |
Molecular Weight | 490.553 |
Exact Mass | 490.253998 |
PSA | 182.96000 |
LogP | -0.69 |
Index of Refraction | 1.583 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |