164365-88-2
164365-88-2 structure
- Name: Boc-NH-C4-Br
- Chemical Name: tert-butyl N-(4-bromobutyl)carbamate
- CAS Number: 164365-88-2
- Molecular Formula: C9H18BrNO2
- Molecular Weight: 252.149
- Catalog: Organic raw materials Amino compound Oxy-containing amino compound
- Create Date: 2018-12-24 18:13:55
- Modify Date: 2024-01-11 19:54:31
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Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | tert-butyl N-(4-bromobutyl)carbamate |
|---|---|
| Synonyms |
4-bromobutylamine tert-butylcarbamate
N-Boc 4-bromobutan-1-amine tert-butyl 4-bromobutylcarbamate Carbamic acid, N-(4-bromobutyl)-, 1,1-dimethylethyl ester BrCH2CH2CH2CH2NHBoc 2-Methyl-2-propanyl (4-bromobutyl)carbamate MFCD06201020 N-(4-Bromobutyl)-Carbamic Acid 1,1-Dimethylethyl Ester tert-Butyl (4-bromobutyl)carbamate |
| Description | Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 308.8±25.0 °C at 760 mmHg |
| Molecular Formula | C9H18BrNO2 |
| Molecular Weight | 252.149 |
| Flash Point | 140.5±23.2 °C |
| Exact Mass | 251.052078 |
| PSA | 38.33000 |
| LogP | 2.78 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.473 |
| Storage condition | 2-8°C |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R41 |
| Safety Phrases | S26-S39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2924199090 |
| Precursor 8 | |
|---|---|
| DownStream 1 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |