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1460-34-0

1460-34-0 structure
1460-34-0 structure
  • Name: (3S)-3-Methyl-2-oxopentanoic acid
  • Chemical Name: 3-methyl-2-oxovaleric acid
  • CAS Number: 1460-34-0
  • Molecular Formula: C6H10O3
  • Molecular Weight: 130.142
  • Catalog: Research Areas Others
  • Create Date: 2018-02-23 08:00:00
  • Modify Date: 2024-01-09 01:52:54
  • 3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin, and also an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.

Name 3-methyl-2-oxovaleric acid
Synonyms EINECS 215-955-0
MFCD00002582
(3S)-3-Methyl-2-oxopentanoic acid
2-KETO-3-METHYLVALERIC ACID
Pentanoic acid, 3-methyl-2-oxo-, (3S)-
2-Oxo-3-methylvaleric acid
3-METHYL-2-OXOVALERIC ACID
METHYLETHYLPYRUVIC ACID
Description 3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin, and also an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.
Related Catalog
Target

Human Endogenous Metabolite

Density 1.1±0.1 g/cm3
Boiling Point 190.5±9.0 °C at 760 mmHg
Melting Point 42°C
Molecular Formula C6H10O3
Molecular Weight 130.142
Flash Point 82.2±0.0 °C
Exact Mass 130.062988
PSA 54.37000
LogP 0.17
Vapour Pressure 0.2±0.8 mmHg at 25°C
Index of Refraction 1.438
Storage condition Refrigerator

Section I.Chemical Product and Company Identification
Chemical Name 3-Methyl-2-oxovaleric Acid
Portland OR
Synonym
2-Keto-3-methyl-n-pentanoic Acid
Chemical Formula
CH 3 CH 2 CH(CH 3 )COCOOH
CAS Number
1460-34-0
(International)

Section II.Composition and Information on Ingredients
Chemical NameCAS Number Percent (%)TLV/PELToxicology Data
3-Methyl-2-oxovaleric AcidMin. 90.0Not available.Not available.
1460-34-0
(Tit.)

Section III.Hazards Identification
Acute Health Effects
Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system . Inflam m ation of
the eye is characterized by redness, w atering, and itching. Skin inflam m ation is characterized by itching, scaling,
reddening, or, occasionally, blistering.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Chronic Health EffectsCARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY : Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.

Section IV.First Aid Measures
Eye Contact
C heck for and rem ove any contact lenses. In case of contact, im m ediately flush eyes w ith plenty of w ater for at least 15
minutes. Get medical attention.
Skin Contact
In case of contact, im m ediately flush skin w ith plenty of w ater. Rem ove contam inated clothing and shoes. W ash
clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Inhalation
If the victim is not breathing, perform m outh-to-m outh resuscitation. Loosen tight clothing such as a collar, tie, belt or
w aistband. If breathing is difficult, oxygen can be adm inistered. Seek m edical attention if respiration problem s do not
improve.
Ingestion
IN D U C E V O M ITIN G by sticking finger in throat. Low er the head so that the vom it w ill not reenter the m outh and throat.
Loosen tight clothing such as a collar, tie, belt or w aistband. If the victim is not breathing, perform m outh-to-m outh
resuscitation. Exam ine the lips and m outh to ascertain w hether the tissues are dam aged, a possible in dication that the
toxic material was ingested; the absence of such signs, however, is not conclusive.

Section V.Fire and Explosion Data
Auto-Ignition
FlammabilityNot available.
May be combustible at high temperature.
Flash PointsFlammable Limits
Not available.
Not available.
Combustion Products
These products are toxic carbon oxides (CO, CO2 ).
Fire Hazards
Not available.
Explosion Hazards
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Continued on Next Page
3-Methyl-2-oxovaleric Acid

Section VI.Accidental Release Measures
Spill Cleanup
Irritating material.
InstructionsU se a shovel to put the m aterial into a convenient w aste disposal container. Finish cleaning the spill by rinsing any
contam inated surfaces w ith copious am ounts of w ater. C onsult federal, state, and/or local authorities for assistance on
disposal.

Section VII.Handling and Storage
Handling and Storage
IRRITA N T. REFRIG ERA TE. K eep aw ay from heat. M ech anical exhaust required.W hen not in use, tightly seal the
container and store in a dry, cool place. Avoid excessive heat and light. Do not breathe dust.
Information
Always store away from incompatible compounds such as oxidizing agents.

Section VIII.Exposure Controls/Personal Protection
Engineering Controls
U se process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recom m ended exposure lim its. If user operations generate dust, fum e or m ist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection
Splash goggles. Lab coat. D ust respirator. Boots. G loves. Suggested protective clothing m ight not be sufficient;
consult a specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Exposure Limits
Not available.

Section IX.Physical and Chemical Properties
Physical state @ 20°CSolubility
Solid. (White Lumps.)
Not available.
Specific GravityNot available.
Molecular WeightPartition Coefficient
130.14
Not available.
Boiling PointVapor Pressure
84°C (183.2°F) @ 18 mmHgNot applicable.
Melting PointVapor Density
42°C (107.6°F)Not available.
Refractive IndexVolatility
Not available.Not available.
Critical TemperatureOdor
Not available.Not available.
ViscosityTaste
Not available.Not available.

Section X.Stability and Reactivity Data
Stability

This material is stable if stored under proper conditions. (See Section VII for instructions)
Conditions of Instability
Avoid excessive heat and light.
Incompatibilities
Reactive with oxidizing agents.

Section XI.Toxicological Information
RTECS Number
Not available.
Routes of Exposure
Eye Contact. Ingestion. Inhalation.
Toxicity Data
Not available.
Chronic Toxic EffectsCARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY : Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
Acute Toxic Effects
Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system . Inflam m ation of
the eye is characterized by redness, w atering, and itching. Skin inflam m ation is characterized by itching, scaling,
reddening, or, occasionally, blistering.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Continued on Next Page
3-Methyl-2-oxovaleric Acid

Section XII.Ecological Information
Ecotoxicity
Not available.
Environmental Fate
Not available.

Section XIII.Disposal Considerations
Waste DisposalRecycle to process, if possible. C onsult your local regional authorities. You m ay be able to dissolve or m ix m aterial w ith
a com bustible solvent and burn in a chem ical incinerator equipped w ith an afterburner and scrubber system . O bserve all
federal, state and local regulations when disposing of the substance.

Section XIV.Transport Information
DOT Classification
Not a DOT controlled material (United States).
PIN Number
Not applicable.
Proper Shipping Name
Not applicable.
Packing Group (PG)
Not applicable.
DOT Pictograms

Section XV.Other Regulatory Information and Pictograms
TSCA Chemical Inventory
T h is p r o d u c t is NOT o n t h e E P A T o x ic S u b s t a n c e s C o n t r o l A c t (T S C A ) in v e n t o r y . T h e f o llo w in g n o t ic e s a r e r e q u ir e d b y 4 0
(EPA)CFR 720.36 (C) for those products not on the inventory list:
(i) These products are supplied solely for use in research and developm ent by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determ ined. A ny inform ation that is or becom es available w ill
be supplied on an MSDS sheet.
WHMIS Classification
Not available. Not available.
(Canada)
EINECS Number (EEC)
215-955-0
EEC Risk Statements
R36/37/38- Irritating to eyes, respiratory system and skin.
Japanese Regulatory Data
ENCS No. (2)-1503

Section XVI.
Version 1.0
Validated on 3/1/2007.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39-S36