Shanghai Nianxing Industrial Co., Ltd
China
Product Name: D-Isoleucine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

GL Biochem (Shanghai) Ltd.
China
Product Name: H-D-Allo-Ile-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: D-Isoleucine
Price: ￥808.0/1g ￥278.0/250mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: D-Isoleucine
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Nanjing Peptide Biotech Ltd
China
Product Name: H-D-Ile-OH
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

319-78-8

319-78-8 structure

319-78-8 structure

Name: D-Isoleucine
Chemical Name: D-isoleucine
CAS Number: 319-78-8
Molecular Formula: C₆H₁₃NO₂
Molecular Weight: 131.173
Catalog: Biochemical Common amino acids and protein drugs
Create Date: 2018-09-21 18:30:51
Modify Date: 2024-01-02 09:30:11
D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine[1].

Name	D-isoleucine
Synonyms	(R)-Isoleucine D-Isoleucine EINECS 206-269-2 D-(-)-Isoleucine H-D-Allo-Ile-OH MFCD00064221 H-D-Ile-OH (2R,3R)-2-Amino-3-methylpentanoic acid (2R (3R)-2-Amino-3-methylpentanoic acid

Description	D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Rosenberg D, et, al. Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity. J Neurosci. 2013 Feb 20;33(8):3533-44.

Density	1.0±0.1 g/cm3
Boiling Point	225.8±23.0 °C at 760 mmHg
Melting Point	272-274ºC
Molecular Formula	C₆H₁₃NO₂
Molecular Weight	131.173
Flash Point	90.3±22.6 °C
Exact Mass	131.094635
PSA	63.32000
LogP	0.73
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.463

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NR4700000

CHEMICAL NAME :: Isoleucine, D-

CAS REGISTRY NUMBER :: 319-78-8

BEILSTEIN REFERENCE NO. :: 1721793

LAST UPDATED :: 199803

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

WISWESSER LINE NOTATION :: QVYZY2&1 -D

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6822 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 64,319,1956

Hazard Codes	Xn
Risk Phrases	R40
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NR4700000
HS Code	2922499990

Precursor 7
1460-34-0 66277-23-4 922-63-4 96-17-3
328-39-2 319-78-8 61548-98-9
DownStream 10
1115-24-8 42880-22-8 1730-92-3 73-32-5
319-78-8 1730-91-2 2546-69-2 96-17-3
96-15-1 35590-81-9

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%