99519-84-3

99519-84-3 structure

Name: L-651,582
Chemical Name: 5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]triazole-4-carboxamide
CAS Number: 99519-84-3
Molecular Formula: C₁₇H₁₂Cl₃N₅O₂
Molecular Weight: 424.67
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2018-10-12 10:10:41
Modify Date: 2024-01-04 12:12:41
Carboxyamidotriazole (L 651582; CAI) is a blocker of non-voltage dependent calcium channel[1]. Carboxyamidotriazole (L 651582; CAI) is a non-cytotoxic anti-tumor drug, which also shows anti-inflammatory activity[2].

Name	5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]triazole-4-carboxamide
Synonyms	4-CAI CAI Carboxyamido-triazole Carboxyamidotriazole

Description	Carboxyamidotriazole (L 651582; CAI) is a blocker of non-voltage dependent calcium channel[1]. Carboxyamidotriazole (L 651582; CAI) is a non-cytotoxic anti-tumor drug, which also shows anti-inflammatory activity[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	Calcium channel[1]
References	[1]. Chen C, et al. Carboxyamidotriazole Synergizes with Sorafenib to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229. [2]. Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63.