24558-60-9

24558-60-9 structure

Name: Sphingosine (d14:1)
Chemical Name: (2S,3R,4E)-2-Amino-4-tetradecene-1,3-diol
CAS Number: 24558-60-9
Molecular Formula: C₁₄H₂₉NO₂
Molecular Weight: 243.38600
Catalog: Signaling Pathways Epigenetics PKC
Create Date: 2017-07-15 08:58:44
Modify Date: 2024-01-10 17:52:13
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters[1].

Name	(2S,3R,4E)-2-Amino-4-tetradecene-1,3-diol
Synonyms	Tetradephing-4-enine D-erythro-C14-sphingosine (E)-D-erythro-2-AMino-4-tetradecene-1,3-diol C14-Sphingosine (2S,3R,E)-2-Amino-4-tetradecene-1,3-diol (2S,3R)-amino-tetradeca-4-ene-1,3-diol

Description	Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> TGF-beta/Smad >> PKC
Target	PKC
References	[1]. Y A Hannun, et al. Regulation of protein kinase C by sphingosine and lysosphingolipids. Clin Chim Acta. 1989 Dec 15;185(3):333-45.