908258-44-6
908258-44-6 structure
- Name: Benzyl-PEG10-alcohol
- Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- CAS Number: 908258-44-6
- Molecular Formula: C27H48O11
- Molecular Weight: 548.66300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-01-14 07:08:48
- Modify Date: 2024-01-02 17:26:50
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Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
|---|---|
| Synonyms |
decaethylene glycol monobenzyl ether
1-Phenyl-2,5,8,11,14,17,20,23,26,29-decaoxahentriacontan-31-ol |
| Description | Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C27H48O11 |
|---|---|
| Molecular Weight | 548.66300 |
| Exact Mass | 548.32000 |
| PSA | 112.53000 |
| LogP | 1.34490 |
|
~%
908258-44-6 |
| Literature: CHUGAI SEIYAKU KABUSHIKI KAISHA Patent: EP1854792 A1, 2007 ; Location in patent: Page/Page column 207-208 ; |
