1010-93-1

1010-93-1 structure

Name: Metronidazole acetic acid
Chemical Name: 2-(2-methyl-5-nitroimidazol-1-yl)acetic acid
CAS Number: 1010-93-1
Molecular Formula: C₆H₇N₃O₄
Molecular Weight: 185.13700
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2016-05-19 00:07:11
Modify Date: 2024-01-08 12:19:02
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa[1][2][3].

Name	2-(2-methyl-5-nitroimidazol-1-yl)acetic acid
Synonyms	2-Methyl-5-nitro-1H-imidazole-1-acetic acid 1-Carboxymethyl-2-methyl-5-nitro-imidazol 2-methyl-5-nitroimidazole-1-acetic acid Metronidazole acetic acid

Description	Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. M Chacko, et al. Studies on the Possible Mutagenic Action of Metronidazole. Indian J Exp Biol. 1987 Apr;25(4):240-3. [2]. M D Mudry, et al. Mutagenic Bioassay of Certain Pharmacological Drugs: III. Metronidazole (MTZ). Mutat Res. 1994 Mar 1;305(2):127-32. [3]. In Schaechter, M.; Engleberg, N. C.; DiRita, V. J. et al. Schaechter's Mechanisms of Microbial Disease. Hagerstown, MD: Lippincott Williams & Wilkins. p. 28.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Phrases	36
Safety Phrases	26
RIDADR	NONH for all modes of transport
HS Code	2933290090

443-48-1

~62%

1010-93-1

Literature: Journal of Heterocyclic Chemistry, , vol. 45, # 3 p. 921 - 925

56910-52-2

~13%

1010-93-1

Literature: WO2014/7650 A1, ; Page/Page column 54; 55 ;

1016-40-6

1010-93-1

Literature: European Journal of Medicinal Chemistry, , vol. 45, # 2 p. 661 - 666

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%