35959-37-6
35959-37-6 structure
- Name: 5’-Azido-2’,5’-dideoxyuridine
- Chemical Name: 1-[(2R,4S,5R)-5-(azidomethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
- CAS Number: 35959-37-6
- Molecular Formula: C9H11N5O4
- Molecular Weight: 253.21
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-09-19 13:11:49
- Modify Date: 2024-02-05 17:39:26
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5’-Azido-2’,5’-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 1-[(2R,4S,5R)-5-(azidomethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione |
|---|---|
| Synonyms |
5'-N3-2'-dU
5'-Azido-2'-deoxyuridine 5'-azido-2',5'-dideoxyuridine Uridine,5'-azido-2',5'-dideoxy |
| Description | 5’-Azido-2’,5’-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C9H11N5O4 |
|---|---|
| Molecular Weight | 253.21 |
| Exact Mass | 253.08100 |
| PSA | 134.33000 |
|
~81%
35959-37-6 |
| Literature: Hiebl, Johann; Zbiral, Erich; Balzarini, Jan; Clercq, Erik De Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1426 - 1430 |
|
~59%
35959-37-6 |
| Literature: Henn; Garnett; Chhabra; Bycroft; Baldwin Journal of Medicinal Chemistry, 1993 , vol. 36, # 11 p. 1570 - 1579 |
|
~%
35959-37-6 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
|
~%
35959-37-6 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
|
~%
35959-37-6 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
|
~%
35959-37-6 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
