Name | h-lys-d-pro-thr-oh |
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Synonyms |
l-lysyl-d-prolyl-l-threonine
l-lys-d-pro-l-thr lys-d-pro-thr interleukin 1b antagonist [D-Pro194]-IL-1 b (193-195) (human) |
Description | Lys-D-Pro-Thr, an IL-1beta analogue, is a potent IL-1 inhibitor. Lys-D-Pro-Thr inhibits the protective effects of IL-1 beta[1][2]. |
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Related Catalog | |
Target |
IL-1 |
In Vivo | Lys-D-Pro-Thr (10 mg/kg; 腹腔给药; 持续 4 天) 抑制 fMLP (HY-P0224) 和 MMK-1 (HY-P1117) 对依托泊苷 (HY-13629) 诱导脱发的保护作用[1]。 Animal Model: 11-d-old rats[1] Dosage: 10 mg/kg Administration: IP; for 4 days Result: Inhibited the protective effect of fMLP and that of MMK-1 against Etoposide-induced alopecia. It alone did not induce alopecia. |
References |
Density | 1.288g/cm3 |
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Boiling Point | 691.3ºC at 760mmHg |
Molecular Formula | C15H28N4O5 |
Molecular Weight | 344.41 |
Flash Point | 371.9ºC |
Exact Mass | 344.20600 |
PSA | 158.98000 |
LogP | 0.11330 |
Vapour Pressure | 4.12E-22mmHg at 25°C |
Index of Refraction | 1.56 |
Safety Phrases | 22-24/25 |
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