39959-66-5
39959-66-5 structure
- Name: LY 78335
- Chemical Name: 1-(2,3-dichlorophenyl)ethanamine,hydrochloride
- CAS Number: 39959-66-5
- Molecular Formula: C8H10Cl3N
- Molecular Weight: 226.53100
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2017-04-24 10:01:41
- Modify Date: 2024-04-05 11:14:39
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1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].
| Name | 1-(2,3-dichlorophenyl)ethanamine,hydrochloride |
|---|---|
| Synonyms | DCMB hydrochloride |
| Description | 1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1]. |
|---|---|
| Related Catalog | |
| In Vivo | 1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats [1]. Animal Model: Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats[1] Dosage: 50 mg/kg Administration: Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days Result: Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats. |
| Molecular Formula | C8H10Cl3N |
|---|---|
| Molecular Weight | 226.53100 |
| Exact Mass | 224.98800 |
| PSA | 26.02000 |
| LogP | 4.51540 |